BioNumerics is a powerful bioinformatics software suite used globally for managing, analyzing, and visualizing biological data. To unlock its full potential, you must correctly apply your software license.
: Open BioNumerics. If it is a new installation, a licensing prompt may appear automatically.
If your computer is connected to the internet, select this option. The software will contact the Applied Maths secure licensing server and instantly activate your product.
If the workstation lacks internet access, you may need to generate an Activation Request file within the software, transfer it to an internet-enabled machine, and upload it to the vendor's license portal to receive a final license file. 4. Verify the Installation bionumerics license string install
If you are using (for existing customers):
Open Command Prompt (as Admin) and type:
Check for hidden trailing spaces or missing characters. Manually verify that dashes are preserved. "Access Denied / Cannot Write License File" BioNumerics is a powerful bioinformatics software suite used
: For MLST (Multilocus Sequence Typing) and whole genome sequence analysis. Database Management
Upon successful validation, a confirmation message will display your license number, expiration date (if applicable), and enabled modules. 4. Restart the Application Close the License Manager.
| Error Message | Likely Cause | Solution | | :--- | :--- | :--- | | | Typo, extra spaces, or line breaks. | Re-paste the string into Notepad first to strip formatting. Copy again. | | "Host ID mismatch" | The license was generated for a different MAC address or dongle. | If you changed network cards or use Wi-Fi vs Ethernet, regenerate the license with the current active adapter’s MAC. Disable Wi-Fi if using Ethernet. | | "License expired" | Subscription license date passed. | Contact bioMérieux for renewal; generate a new string. | | "No such feature" | The license string does not include a module you are trying to use. | Install only the modules you purchased. Uncheck others in the module selector. | | "Cannot write license file" (Permission denied) | User lacks write access to ProgramData or registry. | Run BioNumerics as Administrator. Right-click the installation folder > Properties > Security > grant Full Control to Users. | | "License server not found" (Floating license only) | The client cannot see the server hosting the license. | On the server, ensure port 27000-27009 is open. On the client, set @serverhostname in the license string. | If it is a new installation, a licensing
: Includes tools for regional and national database connectivity. PulseNet International troubleshoot connectivity between a BioNumerics client and its license server? Bionumerics Databases - PulseNet International
If you purchased a single-user license, the string is saved directly on your local workstation. The software creates a local license file ( .lic ) within the BioNumerics installation directory. Network (Server) License
: If your license is tied to a physical USB hardware key, ensure the latest drivers are installed from the Sentinel/Gemalto support site before entering the license string. Internet Connectivity